Designed to support efficiency at the point of care, UpToDate Pro Plus1 includes Expert AI decision support plus advanced tools designed to simplify CME compliance, support complex prescribing decisions, and keep trusted clinical information accessible for wherever care happens.
Choose the package that best fits your needs:
NEW Package Option
New UpTODate Expert AI Feature
Make confident, informed care decisions with the clinical GenAI solution that goes beyond quick answers. Designed by clinicians who understand the complexities of care, UpToDate Expert AI delivers evidence-based recommendations that reflect real-world clinical practice through a conversational interface that supports clinical reasoning and empowers your expertise.
Advance clinical care with the AI-powered UpToDate Pro Plus package, now available as a package option for professional subscribers in the United States and Canada.
Personalized recommendations from Expert AI connect you to the relevant insights you need faster, supporting real-time clinical decision making.
Detailed, context-aware responses explain the why and how of every recommendation. UpToDate Expert AI supports critical thinking while helping you interpret evidence, close gaps, and appropriately apply insights to patient care.
Built on AI principles that prioritize transparency, evidence, and clinical integrity, every Expert AI response is grounded in evidence and the expertise of 7,600 clinicians. Transparent sourcing allows you to trace information back to UpToDate topics, and encourages deeper clinical thinking and safer care decisions.
Designed to think like a clinician, UpToDate Expert AI offers a natural, conversational experience that mirrors how you’d get advice from a trusted colleague. It goes beyond quick answers by highlighting key assumptions, anticipating common missteps, and explaining the rationale behind each recommendation.
UpToDate Pro Plus featuring Expert AI is currently available only in the United States and Canada as part of a limited market release. We are working to gradually expand access to more countries.
Complete the form at the bottom of the page to get notified when we roll out UpToDate Pro Plus to your country.
If you're an existing individual subscriber in the United States or Canada and would like to upgrade to UpToDate Pro Plus, visit store.uptodate.com, log in to your account, and select the ‘Upgrade to UpToDate Pro Plus’ button.
The UpToDate Pro Plus package includes the same evidence-based clinical content available in a core UpToDate personal subscription, plus new features including:
UpToDate Pro Plus is not available for trainee subscribers, however personal trainee subscriptions in the United States and Canada now include access to UpToDate Expert AI, our new GenAI clinical solution. You also have the option to enhance your subscription by purchasing select add-on features that are part of the UpToDate Pro Plus package, including:
These features are available for an additional fee per add-on.
Yes, personal subscriptions to UpToDate packages include access to our intuitive mobile app, allowing you to access our evidence-based medical resource anytime, anywhere. And, with MobileComplete included in an UpToDate Pro Plus subscription, you can access clinical content offline. You can also sign in to UpToDate through your mobile web browser.
UpToDate offers select drug content from our included reference, UpToDate Lexidrug. All personal UpToDate subscriptions include select medication monographs and tools for medical calculations, dosing, and drug-to-drug interactions screening.
UpToDate runs on desktop and mobile web browsers, and the UpToDate mobile app (iOS/Android), for easy, convenient access across devices.
Yes, you can earn CME/CE/CPD credits when you research topics within UpToDate. Learn why medical professionals choose UpToDate for CME/CE/CPD.
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