Advance clinical care with UpToDate Pro Plus, featuring the Expert AI tool for medical professionals

Medical information changes fast, and as patient care grows more complex, clinicians face constant pressure to keep pace. Balancing speed and accuracy requires a clinical resource that is current, expert-guided, and provides the nuance and context necessary for confident decisions at the point of care.

Built on trusted, evidence-based content from UpToDate, the new UpToDate Pro Plus package sets a new standard in care.

Accelerate care decisions with clinical GenAI

UpToDate® Expert AI delivers responses grounded in evidence.

Simplify complex prescribing

Tools for kidney dosing and antidepressant switching help reduce risk.

Access clinical content anytime, anywhere

MobileComplete™ keeps you connected to trusted content, even without internet.
Compare UpToDate subscription plans for medical professionals

Choose the package that best fits your needs:

For Medical professionals

UpToDate

$579 /year Starting price
Compare Plans and Pricing
Compare Plans and Pricing

UpToDate core features

  • 13,000+ clinical topics, 10,000+ graded recommendations, and 39,000+ graphics across 25 specialties
  • Interactive, evidence-based guides and laboratory monographs with accompanying static algorithms
  • Ability to earn CME/CE/CPD credit while researching topics
  • Online access from any device

NEW Package Option

for medical professionals

UpToDate Pro Plus

$699 /year Starting price
Compare Plans and Pricing
Compare Plans and Pricing

UpToDate core features

  • 13,000+ clinical topics, 10,000+ graded recommendations, and 39,000+ graphics across 25 specialties
  • Interactive, evidence-based guides and laboratory monographs with accompanying static algorithms
  • Ability to earn CME/CE/CPD credit while researching topics
  • Online access from any device

UpToDate Pro Plus additional features

  • UpToDate Expert AI
  • Kidney Dosing Tool
  • Rx Transitions for Mental Health Tool
  • MobileComplete™

New UpTODate Expert AI Feature

For residents, fellows, and students

UpToDate Trainee Subscription

$219 / year
Learn More
Learn More

UpToDate core features

  • 13,000+ clinical topics, 10,000+ graded recommendations, and 39,000+ graphics across 25 specialties
  • Interactive, evidence-based guides and laboratory monographs with accompanying static algorithms
  • Online access from any device

New Features

  • UpToDate Expert AI

UpToDate Expert AI: The clinical AI tool for medical professionals

Make confident, informed care decisions with the clinical GenAI solution that goes beyond quick answers. Designed by clinicians who understand the complexities of care, UpToDate Expert AI delivers evidence-based recommendations that reflect real-world clinical practice through a conversational interface that supports clinical reasoning and empowers your expertise. 

Advance clinical care with the AI-powered UpToDate Pro Plus package, now available as a package option for professional subscribers in the United States.

UpToDate Expert AI on a laptop and mobile device

  • Simplify decision making at the point of care

    Personalized recommendations from Expert AI connect you to the relevant insights you need faster, supporting real-time clinical decision making. 

  • Navigate complex clinical cases

    With responses that include reasoning transparency, Expert AI supports critical thinking while helping you interpret evidence, close gaps, and appropriately apply insights to patient care.

  • Support safe, improved care outcomes

    Built on AI principles that prioritize transparency, evidence, and clinical integrity, every Expert AI response is grounded in evidence and the expertise of 7,600 clinicians. Transparent sourcing allows you to trace information back to UpToDate topics, and encourages deeper clinical thinking and safer care decisions.

  • Improve efficiency with GenAI designed for clinical care 

    Designed to think like a clinician, UpToDate Expert AI offers a natural, conversational experience that mirrors how you’d get advice from a trusted colleague. It goes beyond quick answers by highlighting key assumptions, anticipating common missteps, and explaining the rationale behind each recommendation.

Learn More About Expert AI
Learn About Expert AI

Get anytime, anywhere access to advanced decision support tools

Make faster, more confident diagnosis and treatment decisions with a personal subscription to UpToDate Pro Plus
Purchase Now
Product Screenshot of UTD AI on Mobile device.
Access clinical decision support with GenAI on-the-go with the UpToDate mobile app
A personal subscription to UpToDate Pro Plus includes mobile access to all UpToDate content, including UpToDate Expert AI, Kidney Dosing Tool, and Rx Transitions for Mental Health. And, with MobileComplete included with UpToDate Pro Plus, you can download clinical content from UpToDate for offline use, so you can stay connected even with no signal strength or internet connection.
Learn About The Mobile App

UpToDate: Trusted clinical solutions for individuals, enterprises, and everything in between

Get AI-powered clinical decision support for clinicians

Make confident diagnosis and treatment decisions with convenient, personal access to UpToDate Pro Plus, available for individual professional subscribers in the United States.
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Purchase Now
Purchase Now

Clinical GenAI for residents, students, and fellows

UpToDate Expert AI is now included in trainee subscriptions. Access trusted, evidence-based clinical insights through an interactive GenAI experience designed to enhance learning and decision making.

Purchase Now
Purchase Now

Multi-user subscription options for hospitals and institutions

We offer enterprise subscriptions for provider organizations looking to align care teams and health professionals with the latest evidence-based clinical decision support for consistent, improved health outcomes.

Explore UpToDate Enterprise
Explore UpToDate Enterprise

UpToDate Pro Plus FAQs

  • What countries are UpToDate Pro Plus available in?

    UpToDate Pro Plus featuring Expert AI is currently available only in the United States as part of a limited market release. We are working to gradually expand access to more countries.

    Not in the United States? Complete the form to get notified when we roll out UpToDate Pro Plus to your country.

  • How do I upgrade my existing subscription to UpToDate Pro Plus?

    If you're an existing individual subscriber in the United States and would like to upgrade to UpToDate Pro Plus, visit our support page to get assistance with upgrading.

  • What is included in UpToDate Pro Plus?

    The UpToDate Pro Plus package includes the same evidence-based clinical content available in a core UpToDate personal subscription, plus new features including:

    • UpToDate Expert AI: Make fast, informed decisions with the clinical GenAI solution that delivers tailored clinical recommendations through an intuitive, conversational experience.
    • Kidney Dosing Tool: Get quick, trusted renal dosing guidance that supports safe prescribing for patients with kidney impairment.
    • Rx Transitions for Mental Health: Use this tool for detailed support switching patients between antidepressant medications.
    • MobileComplete: allows you to download all UpToDate content directly onto your device for uninterrupted access to UpToDate content regardless of signal strength or internet connection.

  • How can I access UpToDate Pro Plus as a trainee?

    UpToDate Pro Plus is not available for trainee subscribers, however personal trainee subscriptions in the United States now include access to UpToDate Expert AI, our new GenAI clinical solution. You also have the option to enhance your subscription by purchasing select add-on features that are part of the UpToDate Pro Plus package, including:

    These features are available for an additional fee per add-on.

  • Can I access UpToDate Pro Plus on a mobile device?

    Yes, personal subscriptions to UpToDate include access to our intuitive mobile app, allowing you to access our evidence-based medical resource anytime, anywhere. And, with MobileComplete included in an UpToDate Pro Plus subscription, you can access clinical content offline. You can also sign in to UpToDate through your mobile web browser.

  • Does UpToDate offer drug information?

    UpToDate offers select medication content from our included drug reference, UpToDate Lexidrug. All personal UpToDate subscriptions include select medication monographs and tools for medical calculations, dosing, and drug-to-drug interactions screening.

  • What platforms is UpToDate compatible with?

    UpToDate runs on desktop and mobile web browsers, and the UpToDate mobile app (iOS/Android), for easy, convenient access across devices.

  • Can I earn CME with UpToDate Pro Plus?

    Yes, you can earn CME/CE/CPD credits when you research topics within UpToDate. Learn why medical professionals choose UpToDate for CME/CE/CPD.

  1. UpToDate Pro Plus is currently available in the United States as a package option for professionals.
  2. UpToDate Expert AI is available through a personal UpToDate Pro Plus or trainee subscription in the United States, and through select UpToDate Enterprise Edition accounts.
  3. UpToDate Expert AI requires an internet connection and can't be used offline.
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