Continue Your Access to Point-of-Care Clinical Decision Support From UpToDate

The clinical resource you rely on when decisions matter

Maintain uninterrupted access to continuously updated, expert-driven clinical content powered by Expert AI and grounded in evidence, clinical experience, and patient perspective.

Renew your personal UpToDate subscription quickly and easily.

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Expert insights and tools for point of care decision making

Expert insights and tools for point of care decisions

Make faster, more confident decisions with expert-authored content and interactive tools that help you streamline complex calculations, reduce errors, and enhance clinical efficiency.

Actionable recommendations that guide you through complexity or conflicting evidence

Find and apply the relevant information you need with peer-reviewed clinical recommendations that help you understand what to do, how to do it, and why.

Content aligns with evolving evidence and clinical guidelines

Rather than simply summarizing new evidence, the UpToDate editorial team carefully reviews, contextualizes, and anticipates its impact on clinical decision making, for information that aligns with real-world practice.

Professional development built into your practice

Earn CME, CE, and CPD credits while fulfilling MOC and MATE Act requirements. Plus, with CME auto-submission, you can automatically maintain state licensure without manual tracking or submission of CME credits.

Expert AI Overview Video ~2 mins

Get to the right information faster with Expert AI – now included in personal UpToDate subscriptions in the United States

Trusted clinical decision support from UpToDate is now more intuitive —powered by evidence-based clinical content and Expert AI.

Expert AI doesn’t replace UpToDate or your clinical judgment—it reduces the time you spend searching for and reading topics by delivering the essential clinical considerations and recommendations you ask for, all in one fast, conversational experience.

Expert AI interprets your complex questions and delivers fast responses with the relevant information to help you:

Move from symptom, to differential, to next step without searching across multiple UpToDate topics.
Confirm dosing, diagnoses, or treatment plans quickly with direct access to cited evidence.
Understand the clinical rationale behind recommendations without reading through pages of content.

Expert AI for medical professionals

Access Expert AI within UpToDate professional subscriptions in the United States.

Expert AI for Residents, students, and fellows

Expert AI is available in personal trainee subscriptions in the United States and Canada.

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Is an AI tool is right for your practice?

When incorporating generative AI into your clinical workflow, you need a trusted solution that is built for clinical complexity, pulls from trusted sources, and is transparent and trusted for patient care.

The UpToDate Expert AI difference means our GenAI decision support solution is:

Built exclusively on expert-authored UpToDate clinical content.
Independent and unbiased, free from external influence.
Transparent by design—every response is clearly sourced and traceable.
Clinically validated through continuous expert oversight and ongoing review.
Built to reflect real-world clinical reasoning to support complex care decisions.

Upgrade to UpToDate Pro Plus for advanced tools to support efficiency and confidence.

UpToDate Pro Plus includes everything from the standard UpToDate solution you know and trust, plus:

CME state tagged topics for physicians: See which UpToDate topics meet the requirements of your licensed state.
Kidney Dosing Tool: Evidence-based renal dosing recommendations support appropriate treatment adjustments.
Rx Transitions for Mental Health: Antidepressant switching support tool.
MobileComplete: Download UpToDate content onto your mobile device for offline use.

UpToDate Expert AI on a laptop and mobile device