Leading clinical solutions for individuals, groups, and enterprises

Explore our professional- and enterprise-focused suites of evidence-based, expert solutions consisting of UpToDate®, UpToDate® Lexidrug™ (formerly Lexicomp®), UpToDate Patient and Member Engagement (formerly Emmi®), and UpToDate Digital Architect.

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UpToDate Pro Suite
Explore personal and small group subscription options to UpToDate and UpToDate Lexidrug, the leading evidence-based clinical and drug decision support solutions, trusted by over 3 million health professionals worldwide.
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UpToDate Enterprise Suite
Trusted, unified, and innovative evidence-based solutions for clinical decision support (CDS), referential drug information, patient and member engagement, and education for the modern healthcare ecosystem. 
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A new generative AI experience for UpToDate

Introducing UpToDate Expert AI, an innovative generative AI experience that goes beyond other GenAI tools, grounded in our expert-created content. Get faster, trusted evidence-based insights at the point of care.
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Trusted expert editorial content 

The heart of UpToDate is over 7,600 expert clinicians, editors, and reviewers who review and assemble the latest clinical, drug, and patient and member information with academic rigor.
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Access at the point of care  

Available in the EHR, on mobile devices, and in remote locations, UpToDate solutions are available when you need crucial clinical information.  
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Improve health outcomes 

Over 100 research studies agree: UpToDate improves health outcomes. Explore some of the research that has earned the trust of over 3 million global clinicians.
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Continue medical learning with CME 

UpToDate CDS users can earn CME/CE/CPD credits while researching clinical topics, accepted by dozens of accrediting organizations and specialty boards around the globe. 
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Align clinical information 

Help alleviate healthcare staff burnout and fatigue by aligning solutions within clinics, among care teams, and across systems to reduce errors and variability in care. 
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Improve ROI and processes 

Streamline processes with aligned solutions from one trusted vendor and lower costs through improved patient outcomes and lower readmission rates. 
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“UpToDate's impact on the quality of care is impressive… [and] has become indispensable for professional practice. I do not perform any service without having UpToDate opened.” 

– Dr. Eduardo de Oliveira, Supervising Physician of Internal Medicine Residency, Grupo Hospitalar Conceição (GHC), Brazil 

Recognized for excellence and innovation in healthcare solutions

Innovator in clinical decision support 

Frost & Sullivan recognized the UpToDate solutions as a leader in innovation and the application of AI in clinical decision support solutions. 
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Applying Clinical Generative AI into decision support 

As innovation advances, UpToDate is committed to the responsible, collaborative application of Clinical Generative AI in decision support to improve outcomes. 
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Engaging patients with conversational AI 

The UpToDate Patient Engagement solutions were recognized for best practices in conversational artificial intelligence. 
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Three decades of UpToDate
For over 30 years, clinicians around the world have relied on UpToDate to answer key questions when it matters most - even when the evidence isn’t clear. Learn more about this legacy. 
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Clinical authors are the trusted foundation for generative AI adoption
A recent survey shows physicians are optimistic about using Generative AI in healthcare clinical decision-making and patient care, but having a trusted content source is key to adoption.
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Explore the latest insights from UpToDate

  • Article
    Health
    September 19, 2025

    Technology can help meet patients where they are

    As technology advances, providers can leverage digital tools and evidence-based content to help educate and engage patients in their preferred mediums.
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  • Article
    Health
    September 17, 2025

    Building efficiency into care plans and helping care managers fight burnout

    Workflow-integrated solutions help care manager address member needs without becoming overwhelmed by too many applications and tasks.
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  • article
    Health
    September 17, 2025

    How clinical decision tools improve healthcare and potentially reduce malpractice risk

    Explore how clinical decision tools enhance care, improve outcomes, and reduce risk using evidence-based insights.
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  • Article
    Health
    September 15, 2025

    Beyond burnout: How nursing teams across South Korea are driving change

    South Korea's nurses face burnout amid system pressures. CDS tools and systemic reforms can empower them in expanded roles.
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