Von Willebrand Disease: Basic and Clinical Aspects

Provides insights into all aspects of the condition, which, since its discovery, has been extensively studied and the causative factor deficiency, the understanding of the condition and its treatment has greatly improved.

This book summarizes recent research and will help to optimize the management of patients with von Willebrand disease. It describes the important and complex role of von Willebrand factor in hemostasis and thrombosis. In addition to the current understanding of its molecular biology, this book gives particular focus to the association between genetic variants of von Willebrand factor and different von Willebrand disease phenotypes. It also reviews the important area of the obstetric and gynecological manifestations of von Willebrand disease, as well as the treatment of acute bleeding.

Written by an international team of contributors it describes the progress in, and difficulties of diagnosing phenotypes and genotypes. Molecular diagnosis of type 1, type 2 and its subgroups, and type 3 von Willebrand disease are presented as well as discussion of the potential future role of gene therapy.

Von Willebrand Disease: Basic and Clinical Aspects is a valuable resource for hematologists in practice and in training, and specialists in thrombosis and hemostasis.

Platform:

OvidSP

Publisher:

Wiley

Product Type:

Book

Author:

Federici, A; Lee, C.; Berntorp, E.; Lillicrap, D.; Montgomery, R.

ISBN:

978-1-40-519512-6

Specialty:

• Hematology
• Internal Medicine

Language:

English

Edition:

1st

Pages:

268

Publication Year:

2011

Doody's Star Rating®:

Score:

96