UpToDate clinical knowledge powers evidence-based AI for complex decision making

Expert AI combines trusted, expert-authored UpToDate content and generative AI to deliver point-of-care recommendations with clinical reasoning that reflects how you think through diagnosis, evaluation, and treatment.

Ask a clinical question, explore a symptom, or work through a patient scenario with confidence. Expert AI helps you evaluate options and determine next steps faster.

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Now included in all personal UpToDate subscriptions: Expert AI clinical decision support

The point-of-care medical resource that fits your workflow

UpToDate provides an extensive offering of tools and features designed to support your clinical practice and enhance efficiency, all in one convenient resource.

  • Make smarter, faster decisions with UpToDate Expert AI

    The new clinical GenAI solution available in the UpToDate Pro Plus package streamlines clinical decision making. Spend less time searching for answers with fast access to clear, relevant insights through a conversational experience designed to better support how you think and work.

  • Access UpToDate on your mobile device

    Get expert answers wherever you are with our highly rated mobile app — in the hospital, at home, during telehealth consultations, or even on the go with a network connection. For uninterrupted access anywhere, upgrade to MobileComplete™ and download full content directly onto your mobile device.

  • Support outcomes with patient education content

    With informative patient education materials, you can drive trust and improved outcomes by empowering patients to effectively understand and manage their conditions and overall health.

  • Earn CME/CE/CPD credits

    Automatically accrue credits when you research topics in UpToDate, so you can advance your professional development without taking time away from patient care.

  • Tailor UpToDate to fit your workflow

    UpToDate topics are designed to make searching and sharing our vast content quick, easy, and customizable. You can bookmark topics you wish to revisit, view a history of recently reviewed content, and keep track of significant updates to content you view most often. What’s more, your personal activity automatically syncs across all your devices, ensuring a seamless experience. Explore Features. 

  • Reduce medication errors

    Access select medication monographs in UpToDate, including detailed dosing information, medical calculators, and a drug-to-drug interactions checker for safe and effective drug decision support. For more comprehensive drug information and additional tools, explore a full subscription to UpToDate Lexidrug.
  • Case study

  • Customer testimonials

In my opinion, UpToDate is among the best, if not the top, sources of medical information that I regularly rely on to deliver evidence-based care. I utilize it for diagnosing conditions, exploring treatment options, determining medication dosages, and educating patients. It also offers several highly beneficial tools, including medical calculators and management algorithms, which are up-to-date with current clinical guidelines.
AlHassan Khalid AlJafari, MD
I have continuously been a user and subscriber since the mid-1990s. It has been such a valued resource for me since then.
Joseph Nogueira, MD
Thanks to the use of UpToDate, we’ve been able to reduce the time it takes to find the necessary medical information, thereby improving the quality of patient care. It’s an application with a vast amount of information that’s very easy to search.
Adolfo Wachs, MD
UpToDate is this awesome tool where I can very quickly look up pretty much anything that I need to know in the medical world. It’s constantly updated and just trustworthy information that is right at my fingertips.
Libby Dilg, MD 
UpToDate changed completely the way I treat my patients. It’s a platform that combines everything I need and saves me a great amount of time. I use UpToDate every day. It is the best decision I have had in almost 20 years.
Luis Claudio Santos, MD  
We shouldn’t be relying just on our brains because there is so much information out there. The algorithms in UpToDate are one of the best features of helping people to progress through things. I use it on my phone; I use it on the computer. I use it on my iPad. I always have that information at my fingertips.
Diana Kirk, MD

Now in UpToDate Pro Plus: CME State Tagged Topics for physicians 

Meeting state requirements is easier than ever with UpToDate Pro Plus. Clearly see what content counts toward mandatory credits like opioids, pain management, or one-time state mandates with the new tagged topic feature available for physicians in the UpToDate Pro Plus package.

UpToDate offers a variety of personal and small group subscription options that support your clinical and educational needs

UpToDate: Trusted clinical solutions for individuals, enterprises, and everything in between

UpToDate PRO
Get AI-powered clinical decision support for clinicians
Make confident diagnosis and treatment decisions with convenient, personal access to UpToDate Pro Plus, available for individual professional subscribers in the United States.

UpToDate Enterprise
Multi-user subscription options for hospitals and institutions
We offer enterprise subscriptions for provider organizations looking to align care teams and health professionals with the latest evidence-based clinical decision support for consistent, improved health outcomes.

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