Frequently Asked Questions (FAQ): Sentri7 Pharmacy

Sentri7 Pharmacy is an advanced pharmacy surveillance solution designed with a patient-centered workflow to help healthcare systems identify patients at risk of adverse drug events (ADEs), manage opioid use, reduce medication errors, simplify reporting, support compliance initiatives, and optimize medication utilization. By leveraging evidence-based rules and analytics, real-time alerts identify patients that need attention in order to optimize clinical care.

Sentri7 Pharmacy is ideal for care settings such as hospitals and healthcare systems, clinics, and ambulatory surgery centers. It serves pharmacy teams and hospital administrators focused on reducing drug costs, adverse drug effects, and time spent managing compliance, drug shortages, and reporting. Sentri7 enables real-time patient monitoring to improve patient outcomes and ensure operational efficiency.

Sentri7 Pharmacy teams increases the impact of pharmacy teams by offering

• Real-time patient monitoring, surfacing at-risk patients before adverse drug events occur.
• Automated antimicrobial use and resistance (AUR) tracking that strengthens stewardship and reduces the inappropriate antibiotic use that drives resistance and longer patient stays.
• Evidence-based insights that optimize medication use against razor thin margins and reduce unnecessary exposure.
• Continuously maintained content that keeps your program aligned with Joint Commission, Board of Pharmacy, 340B requirements, and CMS506 measure, reducing audit risk and compliance burden.
• One-click documentation and the Pharmacy Analytics dashboard capture every intervention, giving leaders the data to prove clinical and financial value when ROI is unclear.
• Prioritized patient-centered workflows and turnkey clinical content help stretched teams focus where it matters most, easing the strain of staffing shortages and expanding workloads.

Sentri7 stands out with its real-time monitoring of patients, EHR integrations, and comprehensive and customizable rule content library. In addition, the Sentri7 Analytics dashboards help teams optimize outcomes with actionable insights through dynamic reporting that provides a granular view into performance across a hospital or system, by department, by prescriber, and/or by patient-level detail.

Sentri7 Pharmacy is an ONC Certified Health IT and a NHSN-validated solution.

EHR transactional data for patient care flows into Sentri7 Pharmacy. Using sophisticated rule logic, Sentri7 can evaluate patient information in real-time, identifying those at-risk of an adverse drug event and alerting users. This allows the clinician to focus on the most urgent problems first.

Hospitals and health systems rely on Sentri7 to:

• Reduce pharmacy drug spend, manage shortages, and limit errors through medication optimizations.
• Prioritize at-risk patients with real-time monitoring through evidence-based rules to identify and reduce adverse drug events.
• Automate NHSN Antimicrobial Use (AU) and Antimicrobial Resistance (AR) reporting through validated AUR reporting capabilities
• Ease administrative burden of regulatory reporting while staying compliant with national and local requirements
• Access real-time insights for Pharmacy, Opioid Stewardship, and Antimicrobial Stewardship programs to guide continuous improvement.

Yes. By detecting patients at risk early, Sentri7 ensures that interventions and workflows are put in place quickly, reducing the risk of adverse drug events to patients and providing better overall patient care.

Sentri7 enables one-click data submission to NHSN, including additional reporting for AUR and notifiable conditions. As an NHSN-validated solution for antimicrobial use and resistance reporting, Sentri7 simplifies the process and ensures accuracy.

Yes, you can pull in NHSN-reported events. The most commonly used ones are Standardized Antimicrobial Administration Ratio (SAAR).

Dynamic reporting provides a granular view into performance across a hospital or system, department, by prescriber, and patient-level detail:

• Compare medications being prescribed and medication classes between your facilities to ensure compliance with current health system strategies and priorities (identify high and low performers).
• Track cost savings tied to interventions (not specific to drug acquisition costs) to inform medication utilization and manage overall pharmacy spending.
• Interactive Opioid Stewardship analytics dashboard provides real-time monitoring to track opioids by drug, safety metrics (ex. MME>90, naloxone administration), and review concurrent prescribing (ex. opioid + benzodiazepine exposure)
• Comprehensive Antimicrobial Stewardship analytics dashboard to track key metrics in adherence with AMS policies and procedures, AMS utilization by individual prescriber, SAAR benchmarking to facilitate clinician feedback, C. diff report includes positive patients and risk factors, and a real-time, highly customizable antibiogram.

Sentri7’s scalable infrastructure is designed to support large organizations, from regional hospitals to national health systems, by enabling monitoring across multiple sites in a single view. The solution helps pharmacy teams increase their impact on hospital performance by identifying opportunities to reduce inappropriate medication utilization, costs, risk, and mortality while improving care quality, safety, and overall satisfaction. Sentri7 also supports improved clinician adherence to hospital policies and helps organizations maintain compliance with local and national governing bodies.

Sentri7 Opioid Stewardship helps you manage opioid prescribing by monitoring inappropriate opioid use and avoiding preventable opioid-related adverse events. Most hospitals have opioid policies and EHR data, but have difficulty turning that information into a consistent daily process. Sentri7 allows your team to find high-risk opioid patients early, prioritize pharmacist review, documenting interventions, and show leadership where risk and practice variation exist. It does this by allowing clinicians to de-escalate opioid use as needed, initiate multimodal therapies, discontinue in appropriate uses, and track and measure opioid use by patient, provider, and service levels, and opioid administrative rates.

Sentri7 Opioid Stewardship, a part of Sentri7 Pharmacy, tracks cumulative daily MME in near real-time, alerting your team when a patient's opioid exposure crosses evidence-based thresholds. It surfaces high-risk regimens, like concurrent opioid and benzodiazepine use, so pharmacists can intervene early and adjust therapy. The MME values are incorporated into your customized rules and analytics dashboards.

Sentri7 Antimicrobial Stewardship, a part of Sentri7 Pharmacy, helps you decrease the high cost of antimicrobials by monitoring bug drug mismatches and patients on antibiotics without positive cultures. Your team can optimize antibiotic treatments and stop inappropriate antibiotic treatments. Track days of therapy for antibiotic use to verify decreasing usage.

Sentri7 Pharmacy automates antimicrobial use and resistance (AUR) reporting to the National Healthcare Safety Network (NHSN), so your team can submit validated data with one click instead of manual tracking. It calculates your Standardized Antimicrobial Administration Ratio (SAAR), letting you benchmark antimicrobial use against national data and target areas of overuse. Sentri7 also builds antibiogram data that reveals local resistance patterns, giving prescribers the evidence they need to guide therapy and curb resistance across your facility.

Sentri7 Pharmacy partners and integrates with PrecisePK and DoseMeRx to deliver automated, patient-specific dose recommendations using clinical data such as weight, lab values, and creatinine levels. The integrations support vancomycin and 20+ medications across oncology, neurology, cardiology, and antimicrobials, helping teams hit therapeutic targets more precisely while streamlining workflows, supporting AMS goals, and reducing acute kidney injury (AKI) risk.

Sentri7 is implemented through a straightforward, team-based process supported by both technical and clinical subject matter experts. Our teams guide clinical validation, provide workflow support, and offer interactive product training to help new users get up to speed quickly. Sentri7 is designed to work with existing IT infrastructure, helping extract the data needed while minimizing disruption.

Organizations using Sentri7 have reported:

• Fewer adverse drug events, thanks to near real-time monitoring of high-risk medications like anticoagulants, opioids, and insulin.
• Stronger antimicrobial stewardship, including reduced inappropriate antibiotic use and better alignment with CDC Core Elements.
• Significant time savings, through automated antimicrobial use and resistance (AUR) reporting and one-click intervention documentation.
• Demonstrated cost avoidance, driven by evidence-based interventions and optimized drug utilization.
• Higher compliance rates, with support for Joint Commission, CMS, and 340B program requirements.
• Improved pharmacist efficiency, as prioritized worklists and streamlined documentation reduce administrative burden.

Health systems, including St. Dominic Hospital, Baptist Medical Center South, Steward Healthcare, and Southwest Mississippi Regional Medical Center have shared real-world results after adopting Sentri7. Explore their stories to see how these outcomes translate to your facility.

As an ONC Certified Health IT and NHSN-validated solution, Sentri7 Pharmacy simplifies compliance across Board of Pharmacy regulations, Joint Commission (TJC) standards, 340B program requirements, CMS reporting, CDC antimicrobial stewardship guidelines, and state opioid regulations. It automates antimicrobial use and resistance (AUR) reporting, delivers real-time morphine milligram equivalent (MME) monitoring, and standardizes clinical documentation.

Yes, Sentri7 helps reduce costs by enabling earlier interventions, improving medication utilization, reducing unnecessary therapies, and saving pharmacist time through prioritized workflows and automated reporting.

Wolters Kluwer provides comprehensive support through multidisciplinary teams tailored to each organization’s goals:

• Pharmacy Consulting – Shares best practices, workflows, and education tailored to all pharmacy surveillance programs.
• Clinical Team - Provides specialized training and supports adoption across your organization by board-certified IPs who understand your challenges to efficiently support your workflow.
• Customer Success - aligns resources with your objectives, tracks performance metrics, and delivers actionable recommendations to drive continuous improvement.
• Technical Support - available 24/7 with direct contact to technicians with deep knowledge of the products.
• Product Management - Consults with customers to design and implement regular product enhancements to continually improve the solution

Yes. Sentri7 clinical content is continuously maintained by clinical experts and aligned with current guidance from organizations such as The Joint Commission and CDC. Clinical recommendations accompany eligible rules and are supported by industry leading UpToDate LexiDrug content.

Sentri7 is highly adaptable. Organizations can customize existing rules, create new workflows, and tailor alerts based on their clinical priorities without requiring extensive IT involvement.

Sentri7 stands apart as an ONC Certified Health IT and NHSN validated solution, giving your team a trusted foundation for compliance and clinical decision-making that many competitors can't match. Here's what sets it apart:

• Real-time clinical surveillance: Continuously process patient data from your existing electronic health record (EHR) to surface timely intervention opportunities, so your pharmacists act on what matters most.
• A patient-centric workflow: Prioritized worklists and streamlined documentation reduce administrative burden
• A customizable, evidence-based rules library: Edit or add rules without IT intervention
• Customizable analytics dashboards: Surface actionable insights that help teams track performance, identify improvement opportunities, and support quality improvement initiatives.
• 1-click antimicrobial use and resistance (AUR) reporting: Automate NHSN submissions instead of tracking data manually.
• Multidisciplinary support: Dedicated clinical, informatics, and customer success teams help you optimize adoption, track performance, and demonstrate return on investment.

Sentri7 is designed to adapt to the unique needs and structure of your pharmacy surveillance program as your organization evolves. More than a technology solution, Sentri7 is backed by multidisciplinary teams that partner with you to strengthen surveillance efforts, support continuous improvement, and help drive long-term success.

Sentri7 Pharmacy was ranked Best in KLAS 2026 for Pharmacy Surveillance. KLAS Research specializes in monitoring and reporting the performance of healthcare solution providers, and rated Sentri7 as a market leader for hospitals and health systems seeking to optimize pharmacy surveillance programs. Best in KLAS is determined based on the feedback of thousands of providers throughout the last year.

Yes, Sentri7 Pharmacy is certified for AUR reporting by the ONC and listed on the Certified Health IT Product List (CHPL).

CMS has incorporated Antimicrobial Use and Resistance (AUR) reporting to the National Health and Safety Network (NHSN) as a required element under the Public Health reporting category within the Promoting Interoperability Program beginning in 2024. To qualify for the Promoting Interoperability program credit, AUR reports must be submitted to the NHSN by a certified vendor.

Yes, Sentri7 complies with the National Healthcare Safety Network (NHSN) protocols. NHSN requires all production AU Summary Clinical Document Architecture (CDA) files to contain an SDS Validation ID, which the NHSN provides to each vendor after successful validation.