Health November 05, 2026

Healthcare of the future won’t search for intelligence. It will run on it

Key Takeaways

  • Embedding evidence-based clinical decision support directly into the workflow can help clinicians make informed decisions without disrupting care delivery.
  • Combining patient-specific context with trusted clinical intelligence can enable more consistent, efficient, and personalized decision-making.
  • Workflow-integrated solutions can help healthcare organizations scale evidence-based practice across teams while supporting better outcomes and operational performance.
As healthcare grows more complex, the greatest value comes from delivering trusted, patient-specific clinical intelligence directly within the workflow, where it can help enable care teams to make better decisions faster and more consistently.

For decades, healthcare professionals have had to leave their workflow to find answers. Clinicians searched for evidence, pharmacists researched therapies, payers reviewed supporting documentation, and patients navigated fragmented external sources for education.

AI is changing that. Trusted intelligence can now be delivered directly into the moments where decisions happen, helping reduce friction, improve consistency, and support more confident decisions.

At this year’s HLTH event, we’re showcasing how evidence-based clinical, therapeutic, and medication intelligence can be embedded across healthcare workflows, from bedside decision-making and ambient documentation to payer reviews, pharmacy operations, digital health platforms, and patient engagement.

From search to embedded intelligence

Access to information is important, but access alone doesn’t eliminate the challenges of modern care delivery.

Clinicians still navigate growing volumes of data and increasingly complex workflows. Pharmacists must evaluate therapies with confidence. Payers need reliable evidence to support coverage decisions.

Embedding evidence directly into clinical workflows can help make evidence-based guidance easier to access, support adherence to evidence-based practices, and help clinicians make more informed decisions at the point of care. Intelligence moves with the workflow rather than requiring users to stop and search for it.

Bringing intelligence into applications

As healthcare organizations move from experimentation to deployment, the quality of the knowledge behind AI becomes critical.

UpToDate® Expert AI combines the trusted clinical expertise of UpToDate with generative AI capabilities designed for healthcare. Through UpToDate® Connect, healthcare software developers and digital health organizations can use the new UpToDate Expert AI API to embed conversational, AI-generated answers grounded in UpToDate clinical content directly into their products and workflows.

This allows organizations to bring evidence-based answers into clinician, patient, and operational experiences without forcing users to leave the applications they rely on every day, which can introduce unnecessary friction.

The role of therapeutic and medication intelligence in healthcare AI

Medication-related decisions are among the most complex and consequential decisions in healthcare. Adverse drug events cause more than 1.5 million emergency department visits every year in the United States.

As AI becomes more involved in medication-related decisions, the quality of the intelligence supporting those experiences becomes critical to avoid introducing new risk.

At HLTH, we’re highlighting how Medi-Span® provides structured, evidence-based therapeutic and medication intelligence for use across healthcare systems and workflows, and how Medi-Span® Expert AI extends that intelligence to support medication-focused AI experiences.

High-quality therapeutic and medication intelligence helps improve the reliability of AI-generated recommendations, supports more efficient prior authorization and formulary workflows, and helps organizations reduce the risk of decisions based on incomplete or inconsistent medication information.

As organizations across healthcare expand their use of AI, having the right evidence base is a foundational component of responsible, scalable innovation.

Trusted guidance delivered where care happens

Delivering intelligence in the workflow requires a growing ecosystem of partnerships and integrations. Through relationships with organizations such as Epic®, Abridge, Suki, and other healthcare technology innovators, we’re helping bring trusted clinical decision support directly into the environments where care teams already work.

As healthcare becomes more connected, organizations also need solutions that combine trusted evidence with the flexibility to reflect how care is delivered within their own environment. That’s why we’re continuing to focus on capabilities that allow health systems to incorporate local content, operational priorities, and organizational preferences alongside evidence-based recommendations.

By supporting local content, configurable experiences, and evolving workflow integrations, healthcare organizations can make trusted guidance more relevant, actionable, and effective for the people who depend on it.

See what’s next at HLTH

Healthcare of the future won’t depend on users having to search for information. It will depend on trusted intelligence embedded across every workflow, every application, and every decision.

Visit us at HLTH to see how UpToDate Expert AI, UpToDate Connect, Medi-Span, and Medi-Span Expert AI are helping healthcare organizations, technology vendors, and payers bring evidence-based clinical, therapeutic, and medication intelligence directly into the flow of work.

From clinical decision support and ambient documentation to medication-focused AI experiences and digital health platforms, we’re helping make trusted expertise available wherever decisions happen.

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