Trusted, transparent AI answers to support critical medication decisions
Nearly a third of clinicians’ questions (30%) are drug-related, according to traditional UpToDate usage trends. With UpToDate Expert AI, clinicians get more in-depth answers to vital questions from a solid foundation of approximately 3,000 drug topics in the areas most requested by UpToDate users.
The vetted drug topics are written and curated by the pharmacists and clinical experts behind UpToDate Lexidrug. The expanded drug information is also fully harmonized with the trusted content of UpToDate, which supports generative answers that avoid potential issues stemming from outdated or inconsistent sources across the internet.
Similar to a chatbot, clinicians can ask natural language questions about medications such as:
- 30-year-old female needs Arava for rheumatoid arthritis. Is contraception required while taking?
- Does risperidone or aripiprazole have a higher risk of QTc prolongation?
- Allopurinol, spironolactone, lisinopril; which of these medications is causing gynecomastia in my patient?
Continuous feedback loop drives enhancements to UpToDate Expert AI
Fellin added, “This is one of several expansions and enhancements in our roadmap for UpToDate Expert AI. For example, in addition to continuously enhancing speed and usability, we know there is interest in more drug information at point-of-care. Doctors, nurses and health leaders are our north star, and we’ll continue to iterate and enhance based on the feedback and excitement they share.”
UpToDate Expert AI will be demonstrated at the Wolters Kluwer Health booth #1644 at the ASHP (American Society of Health-System Pharmacists) Midyear Clinical Meeting held December 8-10, 2025.
