Post-translational Modification of Protein Biopharmaceuticals

This first authoritative overview of the topic is an indispensable guide for drug developers and drug manufacturers with an interest in protein pharmaceuticals.

From the leading author in the field, known around the world for his work and his authoritative publications, the contents of this book have been selected so as to reflect their relative importance for biopharmaceuticals. As a result, around half of the book is devoted to protein glycosylation, while the remainder is made up of other modifications, such as carboxylation, hydroxylation, sulfation, amidation and proteolytic processing. A final section addresses the latest trend of engineering the modification pattern to improve a given biopharmceutical, presenting several recent case studies of successful posttranslational engineering.

Platform:

OvidSP

Publisher:

Wiley

Product Type:

Book

Author:

Walsh, Gary

ISBN:

978-3-52-732074-5

Specialty:

• Biotechnology

Language:

English

Edition:

1st

Pages:

390

Publication Year:

2009