HealthMarch 05, 2026

5 questions to ask about AI for healthcare

AI-powered solutions will no doubt be the talk of the HIMSS healthcare and technology conference. Leaders and clinical users need to know the right questions to ask when evaluating AI solutions.

There is no denying that the future of healthcare technology – from streamlining workflows to information searches and care delivery support – is being shaped by AI. The enthusiasm from clinicians, administrators, and health consumers is growing. The concern that remains is security and the reliability of open-sourced or unvalidated AI tools:

As AI becomes more pervasive in healthcare workflows, healthcare leaders and clinical users must ask the right questions when evaluating AI-powered solutions. Beyond understanding what an AI tool can do, it’s essential to explore how it addresses real-world concerns like privacy, reliability, and clinical relevance.

Top 5 questions to ask vendors about their healthcare AI solutions

Attendees at the HIMSS 2026 conference can use this practical guide with five key questions to help navigate conversations with vendors and participants, helping them identify AI-enhanced solutions that are not only innovative but also trustworthy and effective in clinical care.

1. How is the AI validated for clinical use?

Understanding how an AI tool and the content it delivers are tested to ensure its reliability and relevance in real-world clinical scenarios is critical. Solutions that combine expert clinical judgment with structured, repeatable evaluation methods can help mitigate some of the concerns that AI use brings to patient care.

2. What safeguards are in place to support patient safety?

The measures taken to identify and mitigate risks, such as harmful recommendations or omissions, are increasingly important, and understanding these safeguards is a priority. Solutions should have rigorous safety assessments and clinician-audited reviews to minimize potential harm.

3. How does the AI incorporate trusted, evidence-based content?

Is the AI is grounded in peer-reviewed, expert-authored content that aligns with established medical practices? Outputs with this sourcing will be clinically sound and relevant to patient care, significantly reducing the risks from outputs based on an unverified or open source.

4. What role do clinicians play in the development and validation process?

Tools meant to support clinicians benefit from having physicians involved in shaping, evaluating, and refining AI. Their expertise is critical to sustaining a tool that reflects real-world clinical reasoning and judgment.

5. How does the AI tool stay current with evolving evidence and innovation?

Explore how the AI adapts to new medical evidence and technological advancements. Continuous validation and feedback loops are essential to maintaining alignment with best practices, consistency, and clinical relevance over time.

Powering the future of healthcare with trusted AI at HIMSS

Join Wolters Kluwer in championing the next generation of care delivery at HIMSS 2026. Explore ways to reach your transformative healthcare goals or set up a meeting with solutions specialists at our HIMSS Info Center. Throughout the conference, we will highlight our commitment to AI built on a foundation of trusted, evidence-based content. To learn more, download The UpToDate Point of Care Report, "Building the bridge—Generative AI and the future of clinical knowledge."

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