HealthJuly 14, 2025

Stay ahead of the 2026 updates for ICD-10 codes

The upcoming 2026 ICD-10 updates, effective October 1, 2025, are set to impact coding workflows for healthcare providers, payers, and analytics systems worldwide. Learn tips to prepare your organization, and avoid costly disruptions from delays in claims processing to compliance risks. 

What you need to know about ICD-10 updates in 2026 

The 2026 ICD-10 updates, released by CMS on June 9, 2025, will take effect on October 1, 2025, and cover processes until September 30, 2026. These updates include:

  • 614 total new codes, including 487 billable
  • 12 invalidated codes
  • 642 changes to billability
  • 88 term modifications
  • 1 new ICD-10 section

It’s no surprise to see updates across the board for the FY 2026 ICD-10-CM code release, including guideline changes and revisions to official notations such as Excludes Notes and Code First/Use additional code, and the addition of new sections and subcategories. Several areas have been expanded for even greater granularity, adding body sites and severity, with many codes changing to parent codes.

These updates allow patient conditions to be documented with greater precision, enabling more accurate clinical decision support, streamlined payer workflows, and deeper insights into population health records. Here is a snapshot of what is coming for October 1st.

New ICD-10 codes for 2026: Non-pressure ulcers

Non-pressure ulcers leads the pack with over 100 new codes broken down to site and severity:

L98.A1 Non-pressure chronic ulcer of upper arm
L98.A11 Non-pressure chronic ulcer of right upper arm
L98.A116 Non-pressure chronic ulcer of right upper arm with bone involvement without evidence of necrosis

Updates to ICD-10 codes for injuries and poisoning

The largest concentration of codes affected Chapter 19: Injury, Poisoning, and Certain Other Consequences of External Causes. The addition of the body site “flank” resulted in over 100 codes spanning injuries from laceration with/without foreign body to open bite.

S31.127 Laceration with foreign body of abdominal wall, left flank without penetration into a peritoneal cavity
S31.117 Laceration without foreign body of abdominal wall, left flank without penetration into peritoneal cavity
S31.156 Open bite of abdominal wall, right flank without penetration into peritoneal cavity
S31.656 Open bite of abdominal wall, right flank with penetration into peritoneal cavity

Chapter 19 also addresses new poisoning, toxic effect, anaphylactic reactions and effects of war codes.

T36.Ax1 Poisoning by fluoroquinolone antibiotics, accidental (unintentional)
T65.841 Toxic effect of xylazine, accidental (unintentional)
T75.83 Effects of war theater
T75.830 Gulf war illness
T78.070 Anaphylactic reaction due to milk and dairy products with tolerance to baked milk
T78.081 Anaphylactic reaction due to egg with reactivity to baked egg

New ICD-10 codes for neurodevelopmental disorders

One new section to come out in this release can be found in Chapter 17: Congenital Malformations, Deformations, and Chromosomal Abnormalities addressing neurodevelopmental disorders related to genetic pathogenic variants.

QA0 Neurodevelopmental disorders, related to specific genetic pathogenic variants
QA0.010 Neurodevelopmental disorders, related to pathogenic variants in ion channel genes
QA0.011 Neurodevelopmental disorders, related to pathogenic variants in glutamate receptor genes
QA0.013 Neurodevelopmental disorders, related to pathogenic variants in other transporter and solute carrier genes

Updates to ICD-10 codes for diabetes

And lastly there is great news on the horizon. Out of the hundreds of codes with this release, probably the most notable and exciting is a single code found in Chapter 4: Endocrine, Nutritional, and Metabolic Diseases.  E11.A – Type 2 diabetes mellitus without complications in remission. Diabetes can now officially be documented as being in remission, classified by sustaining normal blood glucose levels for three months or more! While remission may have always been possible, it's likely becoming more common, and now there's a way to reflect this important clinical detail in the patient record.

This development raises an interesting question: is this shift due to the rise of GLP-1 medications, or are other factors at play? With this new classification, clinical decision support rules will need to be updated, as the guidelines for managing patients in remission will likely differ from those with active diabetes. Additionally, population cohort definitions must be revised to ensure they accurately include or exclude patients based on this new remission status within the diabetes diagnosis.

Impacts of the 2026 ICD-10 updates 

Why are these updates important?

  • Compliance with CMS regulations: Not adopting the new codes can lead to compliance risks.
  • Better patient care: Updated codes ensure accurate diagnosis and treatment planning.
  • Streamlined operations: Latest codes reduce errors in claims and analytics.

Healthcare organizations should act quickly to integrate these updates and avoid disruptions. The 2026 updates won’t just touch upon one part of the healthcare ecosystem; they have widespread implications across key functions, including:

Billing and claims processing: Implementing the new ICD-10 codes correctly is critical to avoiding delays or denials in claims. A missed update could delay payment cycles, as was the case for a large payer in a prior year. Without preparation, they couldn’t process claims by the October 1 deadline, causing costly operational pain points.

Medical documentation: Accurate, up-to-date medical documentation ensures that patient care plans reflect their most current health challenges. For instance, the addition of codes for specific allergies will refine clinical decision-making and reduce safety risks, preventing treatments that could trigger harmful reactions.

Healthcare analytics: The granularity and specificity of new ICD-10 codes fuel precise data analysis. This is vital for tracking population health trends, enhancing risk stratification, and developing value-based care initiatives.

Reporting and compliance: Coding accuracy is a foundational element of compliance with healthcare regulations. Many payer organizations rely on timely ICD updates for accurate patient-data reporting, which has direct implications for reimbursement and compliance audits.

Best practices for adopting ICD-10 updates 

While these updates bring benefits, they also introduce complexity. Updating thousands or tens of thousands of clinical decision support rules, medical policy code groups, or value sets underpinning analytics can be daunting. To ensure smooth implementation of the 2026 ICD-10 updates, organizations should focus on strategic readiness and the appropriate tooling. Here are some proven best practices:

Conduct training sessions: Educate coders, physicians, and billing staff about the updates. Ensure teams understand how changes apply to their specific workflows, improving coding accuracy. Online training modules and CMS resources can be valuable tools.

Automate processes: Traditional methods of updating codes like spreadsheets or generic MDM tools are time consuming and error-prone, lacking the domain-specific knowledge required. Healthcare solutions like the Health Language Platform can help automate ICD-10 updates, reducing processing time for updating affected value sets by up to 90%.

Perform regular audits: Conduct internal audits to identify gaps in your current coding workflows. Use these insights to improve data accuracy, compliance, and operational resilience.

Leverage advanced tools: Adopt healthcare terminology platforms that streamline coding updates. These platforms highlight the specific code groups affected by updates, helping organizations focus efforts where they’re most needed.

Real-world example:
A life insurance company with over 6,000 code groups, previously faced 162 hours of manual work to review updates. With a robust solution, they reduced this task to just 25 minutes for the 2026 ICD-10 updates, enabling them to process updates efficiently and meet compliance requirements.

Strengthen workflows for ICD-10 updates 

The clock is ticking toward October 1, 2025, and preparation is critical. Staying ahead of the 2026 ICD-10 updates means more than just compliance; it’s about strengthening operations and ensuring better outcomes for patients, providers, and payers alike.

By addressing these updates proactively, your organization not only avoids disruptions but also positions itself as a leader in operational efficiency and patient care. We’re here to help you navigate these changes and make the updates as painless as possible for your organization. Reach out today to speak to healthcare data expert.

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