UpToDate Expert AI shown on a laptop and mobile device.

Most AI stops at an answer. UpToDate goes beyond.

Clinical questions aren't always straightforward—clinicians need an AI tool that can handle complex inquiries and provide clear, accountable sources. UpToDate® Expert AI delivers fast, reliable answers through a conversational experience that supports clinical judgment and reasoning.

Purpose-built for today’s clinicians, it combines the power of generative AI with rigorously vetted, expert-authored content from UpToDate—connecting users to the clinical intelligence needed for confident insights.

Note: UpToDate Expert AI is a clinical decision support tool in certain jurisdictions and is a reference-only tool in others.

AI built on clinical content trusted worldwide

UpToDate® Expert AI is generative AI built solely on the trusted, evidence-based UpToDate content used by over 3 million global users and created by over 7,600 clinical experts. Get the nuance, context, and speed clinicians need.

Get fast, traceable clinical answers when you need them

UpToDate Expert AI delivers trusted insights grounded in the evidence-based recommendations from over 7,600 clinicians. Feel confident with rigorous AI standards that prioritize transparency, evidence, and clinical integrity.

Key Features:

  • Succinct answers with the option to refine questions or ask a follow-up.
  • UpToDate sources and inline links provide clear citations for traceable and accountable insights.
  • Ask questions in your language for easy, hands-free inquiries.
  • Localized user experiences in simplified Chinese, Japanese, German, Spanish, and Portuguese.
UpToDate Expert AI screenshot highlighting Sources feature
Sources are listed next to results in UpToDate Expert AI.
UpToDate Expert AI screenshot highlighting Assumptions feature
Assumptions frame the question and clarify the clinical problem.

Conversational AI for better clinical reasoning

Designed to support clinical judgment, not replace it. Every response includes transparent reasoning and clearly stated assumptions, helping you understand the rationale behind insights.

Key Features:

  • Assumptions frame the question and clarify the clinical problem.
  • A side panel provides supporting links, rationale, facts, and UpToDate topics without leaving workflow.
  • Nudges help clinicians add missing context and clarify questions.
  • Inline sources show referenced UpToDate topics tied directly to statements.
  • Accrue CME credits as you ask questions and redeem directly through the platform. See full accreditation details.

Clear responses, even when evidence is unclear

Get nuanced support for interpreting evidence and clinical judgment. Designed to think like a clinician, UpToDate Expert AI empowers your clinical judgment without replacing it.

Key Features:

  • High-quality responses clearly organized into assumptions, direct answers, and clinical context.
  • Tailored visuals simplify complex clinical content.
  • Structured tables help compare care options, such as differential diagnoses.
UpToDate Expert AI on a laptop with the tables magnified.
Tables help compare care options, such as differential diagnoses.

Why you can trust UpToDate Expert AI

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Whitepaper

A measured approach to evaluating clinical AI

Explore how UpToDate Expert AI was purpose-built for healthcare and is assessed for clinical usefulness, knowledge integrity, and potential risks.
Read The Whitepaper 
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Whitepaper

Clinical intelligence for the AI era requires both expert and machine

For the UpToDate clinical team, monitoring the quality of AI-generated responses should always fall on trusted, human expertise. Learn about the Clinical Intelligence Model.
Read About The Model
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report

Report: Trust is the new differentiator in clinical AI

Clinicians and leaders are demanding evidence-based, rigorously evaluated clinical AI systems. In a report, Outsell independently validates how UpToDate extends decades of trusted clinical rigor into the AI era.
Read The Report 

Your clinical mobile AI companion

UpToDate Expert AI is now available as a mobile app in some countries. Download for access on the go.

QR code for App Store download

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Available on the App Store

Available on Google Play

Physician using UpToDate Expert AI on a mobile device.

What global customers are saying

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Norway extends UpToDate partnership with AI pilot
The Norwegian Institute of Public Health extended its commitment to clinicians by adopting UpToDate Enterprise Edition, which will include a pilot of UpToDate Expert AI.
Read The Story
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Advancing responsible AI adoption in the UAE
Dr. Sathyanarayana at Burjeel Hospital says UpToDate Expert AI is “a valuable addition, particularly for quickly addressing clinical queries.”
Read The Story
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Why an NHS doctor feels strongly about responsible AI
For Dr. Emily Audet, to have trust in AI tools, they need to be “as clinically disciplined” as clinicians themselves are expected to be.
Read Her Story

Frequently Asked Questions About UpToDate Expert AI

  • What clinical decision support can UpToDate Expert AI provide?

    UpToDate Expert AI is an interactive GenAI-powered tool built on the evidence-based content from UpToDate. It is designed to equip clinicians with fast, clinically grounded responses that support clinical reasoning, improve efficiency, and help reduce care variability.

    Note: UpToDate Expert AI is considered a clinical decision support tool in certain jurisdictions and is a reference-only tool in others. Availability may vary by region.

  • Who can purchase UpToDate Expert AI?

    UpToDate Expert AI is available to both UpToDate Enterprise and Professional users. Availability and features vary by region.

    • Hospitals and health systems: UpToDate Expert AI is available to clinicians in health systems with an enterprise-wide subscription to UpToDate. Contact us to discuss how you and your health system can get access.
    • Individual clinician subscribers: Expert AI is included in select UpToDate personal professional and trainee subscriptions. Visit the webstore to explore subscription options.

  • Is UpToDate Expert AI available on a mobile device?

    Yes, UpToDate Expert AI is available to all users through the UpToDate mobile app or a mobile web browser. Enterprise users can access through the UpToDate Expert AI mobile app. Visit our mobile apps page for more information.

  • How is UpToDate Expert AI different from the standard UpToDate solution?

    This GenAI solution builds on our legacy of providing trusted clinical answers. It interprets clinical questions, explains reasoning, highlights assumptions, and provides personalized, context-aware recommendations in an intuitive chat format — mirroring a consultation with a trusted expert.

  • What content sources does UpToDate Expert AI use to generate responses?

    Built on the trusted evidence-based content from UpToDate, UpToDate Expert AI draws exclusively from our rigorously maintained clinical information, and developed with AI standards that prioritize transparency, evidence, and clinical integrity. Every answer is traceable and includes direct links to UpToDate topics.

  • How does UpToDate ensure responsible, trusted development of AI capabilities?

    Grounded in expert-driven development, our standards ensure AI tools are designed and validated by clinical professionals, reducing errors and providing evidence-based clinical reasoning.

  • Does UpToDate Expert AI offer CME credits?

    Yes, users can earn CME/CE/CPD credits while they search in UpToDate Expert AI and redeem them directly through the platform. Please note that credits from UpToDate Expert AI are not yet available for certain authorities. See the current accreditation details.

Complete the form to speak to an UpToDate expert

  • See how clinicians can receive trusted AI-generated answers built from UpToDate content with clear sourcing.
  • Get a personalized walkthrough tailored to your organization's clinical and operational needs.
  • Sign up for a trial of UpToDate Expert AI.

Note: UpToDate Expert AI is a clinical decision support tool in certain jurisdictions and is a reference-only tool in others.

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