The trusted evidence-based resource to answer clinical questions

Each patient is unique, and every decision counts. With medicine growing more complex and evidence changing rapidly, it is critical that you have a clinical decision support resource you know you can trust and that is proven to improve patient outcomes.

Providing clarity when you need it most


As a clinician, you find yourself at the intersection of complexity and uncertainty – when the next steps are unclear, and you must make decisions based on the best evidence available to you. This is where UpToDate excels as a clinical decision support resource. We deliver the evidence powered by clinical expertise from the world’s leading physicians — not just for the routine cases, but for the complex and unclear.

Our authors and contributors bring deep domain expertise in the topic discussed and collaborate with our physician editors and peer reviewers to deliver evidence and recommendations that are rich in nuance, yet still clear and actionable. And we deliver it all with technology that helps you quickly get to the answers you need.

doctor paused in hallway looking at UpToDate on tablet

See The Research

More than 80 research studies show that widespread use of UpToDate is associated with improved outcomes and hospital performance.
UpToDate Research Studies

Meet Our Global Experts

With UpToDate, it’s like having the world’s leading physicians in the room with you whenever you need guidance.
UpToDate Physician Authors And Editors

Hear From Our Clinician Users

UpToDate is the go-to resource for clinicians around the world when they need answers, evidence, and expertise they know they can trust.
UpToDate Customer Success Stories

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A step-by-step guide to buying clinical decision support software
How do you select the right CDS solution for your organization — one that will not only provide the actionable, relevant clinical information your clinician care teams trust, but is also easy to use and streamlines the workflow without information overload and clinician burnout?
Explore Our CDS Buyer's Guide
Frequently asked questions about UpToDate evidence-based decision support
What makes UpToDate an evidence-based solution? How does UpToDate decide which evidence to use? Find answers to these questions and more in our FAQ.
FAQs About Evidence-Based Decision Support
Explore UpToDate individual and enterprise subscription options
Choose the category that best describes you so we can help you find option that best matches your needs.
UpToDate Pro
Get anytime, anywhere access for clinicians and small group practices
Make more confident diagnosis and treatment decisions with convenient, personal access to UpToDate with subscription options available for individuals and groups with 2-19 users.
Explore UpToDate Pro
UpToDate Enterprise
Multi-user subscription options for hospitals and institutions
We offer enterprise subscriptions for provider organizations looking to improve outcomes and reduce variations in care.
Explore UpToDate Enterprise
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