Expert content is the foundation of care—responsible, AI-powered clinical intelligence is the future

The healthcare industry is facing a massive technological shift impacting how care is delivered. Generative AI (GenAI) has changed how clinicians search for information—and brings concerns about quality and reliability. Teams also continue to face challenges, including:

  • Information overload
  • Burnout from administrative tasks
  • Financial pressure to transform care delivery

The future of healthcare success will be determined by trust. Leaders want to realize the benefits of AI while mitigating risks to patient safety. That trust needs to be embedded across enterprises like a central nervous system of clinical intelligence, supporting consistent, evidence-based information grounded in expertise.

Meet the new era of UpToDate®. For over 30 years, clinicians around the world have trusted UpToDate and the team of over 7,600 clinical experts for answers. Now, this trusted evidence is integrated across workflows and enhanced with AI, responsibly developed and grounded in our human-driven care recommendations. We are committed to innovating alongside your clinical and governance teams, and equipping the healthcare industry with the evidence-based content of UpToDate, strategically and responsibly powered with AI-enabled technology.

Read Our Vision For GenAI In Healthcare

Our vision for AI-powered healthcare solutions from UpToDate


Evidence and transparency are crucial to building trust in AI technology

Not all GenAI responses are created equal

Applying GenAI to any content without governance and testing can result in challenges such as hallucination, and can negatively impact patient safety. Prioritizing trust in the technology and the evidence-based information foundation is essential–that’s where we come in.

Our clinical experts provide the quality foundation for our AI-powered features. Over three million global clinicians use UpToDate and 99% of users say they trust it as an evidence-based clinical information resource.1 At the heart of this trust is the editorial team of over 7,600 clinical experts who review the latest evidence and lean into their specialized field of expertise to provide the latest clinical information and care recommendations. This content:

  • Must surface trustworthy clinical information
  • Can be enhanced with AI-enabled features like generative responses, query context, natural language questions, and conversational search
  • Must have a mature, responsible testing process to support safe care decisions

This new level of clinical decision support can help clinicians search for information more efficiently and access an extended clinician network in new, innovative ways.

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Physician and consumer surveys: GenAI tools are beneficial if source content is trusted
Two Wolters Kluwer surveys reported physicians and US health consumers see a strong potential for GenAI technology to positively impact healthcare and support better decision-making—but trust in the source content is key for both groups.

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Clinicians can see early benefits to layering AI on expert content

"We are excited to partner with UpToDate to accelerate the responsible use of GenAI in clinical decision support. We share the vision that GenAI must be developed safely, transparently, and on a foundation of trustworthy healthcare content, such as the content provided by UpToDate. Together, we will be testing and validating that GenAI combined with UpToDate offers the ability to get fast, succinct answers in support of delivering better care."

— CMIO, National Health System

Trusting the content

“If I can trust UpToDate to begin with, then getting an AI-powered summary that's coming right from UpToDate—and nowhere else—is going to allow for that increased trust. It's an exciting direction we're heading in.”

— Clinician, Internal Medicine, 5 years of practice

Surfacing answers more quickly

“UpToDate has long provided clinicians with the information they need to make clinical decisions. From what I’ve seen, the combination of UpToDate with GenAI through AI Labs could get clinicians to expert, succinct, evidence-based content even faster.”

— Eric Alper, MD, Senior Vice President, Chief Quality Officer, Chief Clinical Information Officer, UMass Memorial Health

Same content, new delivery

“The information is from a trusted source, but here it’s giving you a new method for querying the data and getting it to point-of-care.”

— Clinician, Internal Medicine, 20+ years of practice

An established trust in UpToDate

“I trust UpToDate. And that level of trust allows me to know that if this is an UpToDate product, I know it's been rigorously tested and it's showing me what it's supposed to show me.”

— Clinician, Internal Medicine, 10 years of practice

Explore more on the future of AI in clinical decision support

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  1. Survey of US physicians who see patients within a large hospital or health system and use a clinical decision support tool, commissioned by Wolters Kluwer Health. N=100. February 2024. Data on file.
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