UpToDate Expert AI is built different. Using it feels like a conversation with a trusted colleague, not an online search. And answers to clinical questions are nuanced and verifiable.
UpToDate has helped clinicians make better decisions for over 30 years. Now in this latest version, new generative AI functionality delivers the most efficient retrieval of UpToDate clinical intelligence – where and when it matters the most.
UpToDate Expert AI is available to select Enterprise Edition accounts in Australia, Canada, Hong Kong, Qatar, South Korea, and the US.
A responsible AI solution for today’s healthcare workforce.
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GenAI with Clinical Intelligence
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Tailored Responses
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Efficiency + Oversight
Built by clinicians, for clinicians.
UpToDate Expert AI is built on technology that draws only from UpToDate content. It prioritises transparency and clinical integrity, and all user feedback is reviewed by UpToDate experts – real humans who are leaders in their fields.
Answers can be traced back to an expert-in-the-loop.
Built to upskill, not deskill.
All GenAI tools can answer questions. But the real question is – can the answer be trusted?
UpToDate Expert AI lists any assumptions made (so the user can agree or adjust their prompt), full clinical reasoning steps, and all sources. The thinking is nuanced and the validation simple.
Supporting clinicians to make better decisions.
Built to find the right evidence, faster.
Doing more with less is a reality of modern healthcare. Another reality is that AI tools are already being used – often in the shadows. Enterprises need responsible enterprise solutions, or they risk introducing unacceptable risk into patient care.
Get workflow speed and good clinical governance.
Report: Shadow AI tool use in healthcare organisations
41% of respondents were aware of colleagues using unauthorised AI tools
17% said they had used an unauthorised tool
Shadow AI occurs when unauthorised AI tools are used across organisations, introducing risk to data, security, and privacy. Leaders at healthcare organisations need to understand how prominent these risks are and take an enterprise approach to AI solutions.
A Wolters Kluwer Health survey of healthcare providers and administrators assessed shadow AI tool usage and the perceived risks of AI solutions. Explore the survey data and actionable steps in the whitepaper, “Shadow AI: A hidden risk to healthcare.”
The latest insights on AI from UpToDate
Conversations on AI & innovation in healthcare
Explore expert-led podcast interviews from UpToDate experts on AI, clinical workflows, and the future of healthcare, offering a thoughtful look at how technology is shaping evidence-based care.
Listen To The PodcastsBuilding the bridge: GenAI and clinical knowledge
Get a special report by Dr. Sheila Bond on how UpToDate is bridging the rigour of clinical knowledge and GenAI innovations. Read our philosophy and the systems built to make GenAI clinically dependable and validated for the point of care.
Read The WhitepaperIn the GenAI era, care delivery relies on trust and efficiency
With trusted, evidence-based clinical intelligence embedded across your health system, your teams can make care decisions confidently in the new era of healthcare.
Read Our Vision
“UpToDate Expert AI harnesses the clinical wisdom of our thousands of expert contributors to think like a clinical colleague—answering complex, highly specific questions with nuance and clarity. The clinical reasoning is unambiguous, drawing solely from Wolters Kluwer evidence-based content, to help doctors confidently keep up with continual changes in medical research.
We are providing a new level of support for better decisions by the care team and better care for patients, while meeting the needs of enterprises for transparency and governance.”
— Peter Bonis, MD, Chief Medical Officer, Wolters Kluwer Health
Good governance
“If we don’t document, don’t validate, and don’t understand the source, we’re not managing risk – we’re creating it.”
— Senior Healthcare Leader, NHS
Trusting the content
“If I can trust UpToDate to begin with, then getting an AI-powered summary that's coming right from UpToDate—and nowhere else—is going to allow for that increased trust. It's an exciting direction we're heading in.”
— Clinician, Internal Medicine, 5 years of practice
Augmenting clinician judgment
“I want supportive decisions as opposed to automated decisions. I'd rather have tools that support my decision-making as opposed to creating it for me and looking for a checkoff that I approve.”
— Physician Assistant, Tier 1 university health system
Transparency in generated responses
“Compared to other products, the transparency in UpToDate Expert AI is 1A. The assumptions section—where it says ‘I’m assuming this patient is not pregnant, not a child, doesn’t have major comorbidities’—puts it above all the other tools I’ve tried.”
— Medical Librarian
An established trust in UpToDate
“I trust UpToDate. And that level of trust allows me to know that if this is an UpToDate product, I know it's been rigorously tested and it's showing me what it's supposed to show me.”
— Clinician, Internal Medicine, 10 years of practice
Explore more on the future of AI in clinical decision support
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Key Challenges
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Whitepapers
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Our Expertise
A generational shift in the workforce
The intersection of innovation, generational workforce shifts, and the emergence of GenAI is driving a new era of clinical information retrieval. Access point-of-care insights.
Get The UpToDate ReportShifting patient expectations
Patients expect more involvement in their care. Including the patient on the care team, with shared, AI-enabled evidence at the center, equips teams for more aligned decisions.
Read The Expert InsightManaging risk and shifting regulation
As healthcare professionals increasingly use GenAI tools in administrative work and at the point of care, leaders must implement usage policies to minimize risk to security and patient care.
Read The Expert InsightHealthcare AI shouldn’t be an ‘either-or’ decision
AI in clinical decision support solutions shouldn't mean compromising between speed, evidence, and trust. Deliver AI solutions that enhance decision-making without tradeoffs.
Read The WhitepaperIntegrating responsible clinical generative AI at the point of care
Artificial intelligence tools represent an exciting new frontier in healthcare, but identifying a responsible, expert content partner is key to clinician adoption.
Access The WhitepaperThe role of real-world evidence in informing clinical decision-making
Numerous AI-powered tools are now available to support clinicians. Health leaders must determine which can cut through the noise to provide the latest evidence-based information for teams.
Access The WhitepaperInnovate responsibly: Cutting through the GenAI hype
In the fast-moving world of GenAI, it’s easy to get caught up in the allure of new technologies. But Dr. Holly Urban says we can’t let hype outpace responsibility without careful vetting.
Read On HIStalkSeeing clinical value from AI requires real-world results
AI-enabled solutions are now important workflow investments, but healthcare leaders must have clarity around implementation, adoption, and business strategy.
Read Dr. Bonis’ ThoughtsRedefining speed with AI
As AI tools further enter the clinical setting, they can provide huge opportunities for time savings through more efficient decision-making.
Read Yaw’s PerspectiveFrequently Asked Questions About UpToDate Expert AI
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What clinical decision support can UpToDate Expert AI provide?
UpToDate Expert AI is an interactive GenAI-powered clinical reasoning tool grounded in the evidence-based content from UpToDate. It helps you think through cases, clarify concepts, and answer clinical questions. -
Who can purchase UpToDate Expert AI?
UpToDate Expert AI is available to both UpToDate Enterprise and Professional users.
- Hospitals and health systems: UpToDate Expert AI is available to clinicians in select health systems through their UpToDate Enterprise Edition subscription. Contact us to discuss how you and your health system can get access.
- Individual subscribers in the United States and Canada: Visit the UpToDate webstore to subscribe to UpToDate Pro Plus or trainee package with Expert AI.
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Is UpToDate Expert AI available on a mobile device?
Yes, you can access it through desktop or the UpToDate mobile app. -
How is UpToDate Expert AI different from the standard UpToDate solution?
This GenAI solution builds on our legacy of providing trusted clinical answers. It interprets clinical questions, explains reasoning, highlights assumptions, and provides personalized, context-aware recommendations in an intuitive chat format — mirroring a consultation with a trusted expert. -
What content sources does UpToDate Expert AI use to generate responses?
Built on the trusted evidence-based content from UpToDate, UpToDate Expert AI draws exclusively from our rigorously maintained clinical information, and developed with AI standards that prioritize transparency, evidence, and clinical integrity. Every answer is traceable and includes direct links to UpToDate topics. -
How does UpToDate ensure responsible, trusted development of AI capabilities?
Grounded in expert-driven development, our standards ensure AI tools are designed and validated by clinical professionals, reducing errors and providing evidence-based, actionable insights.