For clinicians, every second matters when it comes to making safe, effective patient care decisions.
UpToDate has been a trusted partner for over 30 years, helping clinicians with the most complex decisions. Now, innovative AI-powered functionality is layered on top of our care recommendations—created and reviewed by clinical experts—for faster information retrieval when it matters most.
Patient care decisions often aren’t black-and-white. UpToDate Expert AI, a new GenAI solution, offers an innovative experience that goes beyond other tools and mirrors a conversation with a trusted colleague. It’s designed for the modern clinician and draws only from the trusted, expert-created care recommendations.
Align your care teams with AI-powered decision support across your enterprise. Attending HLTH 2025? Schedule a demo at our booth.
Access guidance faster through advanced responses tailored to your needs. UpToDate Expert AI understands complex, highly specific questions that mirror the way clinicians think. It also goes beyond other GenAI tools to provide key assumptions, anticipate common missteps, and explain the rationale, sources, and evidence behind each recommendation.
Human expertise is essential to trusting GenAI responses. UpToDate Expert AI is grounded in the evidence-based recommendations from over 7,600 clinical experts. These fuel the responses, and include considerations, questions to ask, and assumptions.
Practicing clinicians and healthcare partners have also helped test early models through UpToDate Enterprise Edition by providing feedback, testing prompts, and identifying solution improvements. We will continue keeping these partners in the loop to help support future iterations.
Consistent, reliable evidence should be available for every member of your organization, from physicians to nurses to ambulatory team members. UpToDate can scale across your organization through EHR workflows and solution partnerships, and with GenAI, it’s accessible in the medium clinicians prefer to use.
Inconsistent solutions can create security holes, impact governance, and increase care variation. GenAI tools aligned with enterprise decision support—and purpose-built for healthcare—can be an additional method to help improve compliance and reduce care variation.
“In the UpToDate Expert AI, it’s like I’m having conversations that suggest the next question that I should be thinking of, and I find that really helpful.”
— Physician Assistant, Primary Care
Trusting the content
“If I can trust UpToDate to begin with, then getting an AI-powered summary that's coming right from UpToDate—and nowhere else—is going to allow for that increased trust. It's an exciting direction we're heading in.”
— Clinician, Internal Medicine, 5 years of practice
Augmenting clinician judgment
“I want supportive decisions as opposed to automated decisions. I'd rather have tools that support my decision-making as opposed to creating it for me and looking for a checkoff that I approve.”
— Physician Assistant, Tier 1 university health system
Transparency in generated responses
“Compared to other products, the transparency in UpToDate Expert AI is 1A. The assumptions section—where it says ‘I’m assuming this patient is not pregnant, not a child, doesn’t have major comorbidities’—puts it above all the other tools I’ve tried.”
— Medical Librarian
An established trust in UpToDate
“I trust UpToDate. And that level of trust allows me to know that if this is an UpToDate product, I know it's been rigorously tested and it's showing me what it's supposed to show me.”
— Clinician, Internal Medicine, 10 years of practice
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