UpToDate Expert AI shown on a laptop and mobile device.

UpToDate Expert AI: Enterprise GenAI for healthcare professionals


UpToDate Expert AI is built different. Using it feels like a conversation with a trusted colleague, not an online search. And answers to clinical questions are nuanced and verifiable.

UpToDate has helped clinicians make better decisions for over 30 years. Now in this latest version, new generative AI functionality delivers the most efficient retrieval of UpToDate clinical intelligence – where and when it matters the most.

UpToDate Expert AI is available to select Enterprise Edition accounts in Australia, Canada, Hong Kong, Lebanon, Mongolia, Qatar, South Korea, and the U.S.

Learn About UpToDate Enterprise Edition
Learn About UpToDate Enterprise Edition

A responsible AI solution for today’s healthcare workforce.

  • GenAI with Clinical Intelligence

  • Tailored Responses

  • Efficiency + Oversight

Built by clinicians, for clinicians.

UpToDate Expert AI is built on technology that draws only from UpToDate content. It prioritizes transparency and clinical integrity, and all user feedback is reviewed by UpToDate experts – real humans who are leaders in their fields.

Answers can be traced back to an expert-in-the-loop.
UpToDate Expert AI screenshot highlighting Sources feature
"Sources" response section in UpToDate Expert AI.
Built to upskill, not deskill.

All GenAI tools can answer questions. But the real question is – can the answer be trusted?

UpToDate Expert AI lists any assumptions made (so the user can agree or adjust their prompt), full clinical reasoning steps, and all sources. The thinking is nuanced and the validation simple.

Supporting clinicians to make better decisions.
UpToDate Expert AI screenshot highlighting Assumptions feature
“Assumptions”response section in UpToDate Expert AI.
Built to find the right evidence, faster.

Doing more with less is a reality of modern healthcare. Another reality is that AI tools are already being used – often in the shadows. Enterprises need responsible enterprise solutions, or they risk introducing unacceptable risk into patient care.

Get workflow speed and good clinical governance.
UpToDate Expert AI on a laptop with the tables magnified.
Tables in UpToDate Expert AI responses help compare care options quickly.

Frequently Asked Questions About UpToDate Expert AI

  • What clinical decision support can UpToDate Expert AI provide?

    UpToDate Expert AI is an interactive GenAI-powered clinical reasoning tool grounded in the evidence-based content from UpToDate. It helps you think through cases, clarify concepts, and answer clinical questions.

  • Who can purchase UpToDate Expert AI?

    UpToDate Expert AI is available to both UpToDate Enterprise and Professional users.
    • Hospitals and health systems: UpToDate Expert AI is available to clinicians in select health systems through their UpToDate Enterprise Edition subscription. Contact us to discuss how you and your health system can get access.
    • Individual subscribers: Expert AI is included in select UpToDate personal subscriptions. Availability varies by region—visit the webstore to explore subscription options.

  • Is UpToDate Expert AI available on a mobile device?

    Yes, you can access it through desktop or the UpToDate mobile app. 

  • How is UpToDate Expert AI different from the standard UpToDate solution?

    This GenAI solution builds on our legacy of providing trusted clinical answers. It interprets clinical questions, explains reasoning, highlights assumptions, and provides personalized, context-aware recommendations in an intuitive chat format — mirroring a consultation with a trusted expert.  

  • What content sources does UpToDate Expert AI use to generate responses?

    Built on the trusted evidence-based content from UpToDate, UpToDate Expert AI draws exclusively from our rigorously maintained clinical information, and developed with AI standards that prioritize transparency, evidence, and clinical integrity. Every answer is traceable and includes direct links to UpToDate topics.

  • How does UpToDate ensure responsible, trusted development of AI capabilities?

    Grounded in expert-driven development, our standards ensure AI tools are designed and validated by clinical professionals, reducing errors and providing evidence-based, actionable insights.

Request a demo with a member of our enterprise solutions team

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