Trusted intelligence for every medication decision

Every drug decision, from prescribing and dispensing to counseling, administration, policy, and patient self-management, carries responsibility.

The stakes are high: The World Health Organization estimates medication errors cost $42 billion globally each year. As evidence evolves, healthcare professionals need trusted medication intelligence that is evidence-based, continuously updated, and readily accessible wherever medication decisions are made.

The power of aligned medication intelligence

UpToDate Lexidrug and Medi-Span deliver evidence-based medication intelligence—including recommendations, drug interactions, dosing, and complex polypharmacy—to support appropriate drug decisions for patients and members. Medication guidance is also aligned with UpToDate clinical intelligence, helping connect drug and clinical decisions. Using trusted intelligence across departments, organizations, and workflows can support more consistent, evidence-based decisions across the healthcare ecosystem.

UpToDate Lexidrug for Individuals

A personal subscription to UpToDate Lexidrug offers unparalleled referential drug content that empowers you to make the best possible evidence-based medication decisions.
UpToDate Lexidrug For Individuals

UpToDate Lexidrug for Enterprises

Provide access to referential drug content from UpToDate Lexidrug across teams and empower them to make evidence-based medication decisions, even when cases are complex.
UpToDate Lexidrug For Enterprises

Medi-Span Drug Data

Aligned with UpToDate, Medi-Span supports medication decisions with embedded drug data, drug pricing analysis, and AI-ready medication intelligence to support the entire care continuum.
Learn About Medi-Span

Aligned drug decision support and medication intelligence helps you…

Trust consistent guidance

Medication and clinical topics across UpToDate solutions follow rigorous editorial processes and are aligned to support consistency.

Account for individual patient needs

Drug monographs include guidance for adult, pediatric, and geriatric populations, helping inform confident decisions for each patient.

Apply current evidence

Lexidrug continuously evolves with evidence-based information that helps clinicians apply medication guidance to individual patient needs, including dosing, drug interactions, and complex polypharmacy needs.

Navigate complex decisions

Go beyond standard drug information with in-depth guidance for patient and member populations, comorbidities, pregnancy, and other complex considerations.

“Having a trusted source for drug decisions is critical to delivering safe, high-quality healthcare. Using [UpToDate Lexidrug], I am confident that the information we provide to other healthcare professionals is contributing to the best possible outcomes for our patients.”

– Colm Devine, Chief Pharmacist, Letterkenny University Hospital, Ireland

Efficiently access key drug information within clinical decision support

When treating a patient, you need to move quickly while also making the best decisions possible. Likewise, setting policy or evaluating benefits and claims requires precise and efficient choices. Clear, concise drug monographs make it easy to apply the drug information to the decisions at hand. In addition to drug topics, UpToDate grants you access to the following drug databases:

  • General and disease-specific dosing, including evidence-based, off-label dosing
  • Detailed dose adjustments for impaired kidney or liver function, obesity, or toxicity
  • Pediatric and neonatal dosing and drug administration
  • A separate drug interactions program (Lexi-Interact) that provides a more in-depth analysis of drug-drug, herb-drug, and herb-herb interactions
  • Drug adverse effects, warnings, and precautions, including practical details such as premedication information and patient monitoring parameters
  • Drug administration details, including drug brands, available strength, and dosage form information
  • Current FDA Special Alerts and major Health Canada safety communications

The drug information and drug interactions databases in UpToDate and Lexidrug solutions add another level of knowledge to clinical and pharmacological practice, helping improve the quality and safety of care.

Two Asian pharmacists with tablet and pill bottle

Additional solutions with UpToDate Lexidrug

With UpToDate Lexidrug, additional solutions designed for retail pharmacy can enhance efficiency and improve formulary adherence.
Drug reference for retail pharmacy
Provide evidence-based drug content, tools, and tables with an interface geared for the retail environment that allows pharmacists to quickly access the information they need to assist patients.
Learn More
Custom formulary
With thousands of drugs to consider for your patient population and budgetary requirements, having your formulary and policies integrated directly into decision support tools improves safety and efficiency.
Learn More

Insights from the experts

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Pharmacogenomics and the flawed use of race in recommendations
Race continues to be a consideration – albeit a flawed one – on drug labels and testing recommendations. Our ever-improving knowledge of how genomic factors contribute to the observed differences in medication response should mitigate this.
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Supporting effective treatment for infectious disease while combating antimicrobial resistance
By taking a strategic approach to antimicrobial stewardship with evidence-based resources that provide current information on infections and appropriate treatments, healthcare leaders can help guide their clinicians toward combating antimicrobial resistance.
Read The Article
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The importance of adjusting drug dosing for patient-specific factors 
Despite manufacturers labeling recommending a one-size-fits-all, every patient is different, and medications work differently inside different bodies. This requires a more nuanced, individualized approach to drug dosing.
Read The Article

Explore more insights on drug decision support

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