UpToDate Expert AI on a laptop and mobile device

Generative AI for medical professionals

Not all AI is created equal.

For patient care, clinicians need more than a general-purpose AI tool. Clinical decision making requires a solution built on trusted sources and continuously updated evidence that reflects the complexities of real-world care.

UpToDate® Expert AI combines clinician-authored UpToDate content with evidence-based AI to support clinical judgment and reasoning in complex patient care decisions.

UpToDate Expert AI is currently available in select markets. It is a clinical decision support tool in the United States and certain other jurisdictions, and is a reference-only tool in others.

Work through complex cases with confidence

Move from symptom or question to suggested next steps at the point of care efficiently even when evidence is limited, or the answer is not obvious.

ddx for 49yo pt with chronic high‑dose steroids, vasculitis, brain lesions, lung masses on chest CT.

UpToDate Expert AI product screenshot showing an AI generated response on a mobile phone that reads: You are asking for a differential diagnosis for a 49-year-old patient with vasculitis on chronic high-dose steroids who has brain lesions and lung masses on chest imaging. I am assuming the patient is immunocompromised from chronic high-dose corticosteroids and the "brain lesions" are enhancing mass lesions on MRI.
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    UpToDate Expert AI product screenshot showing an AI generated response on a mobile phone that reads: You are asking for a differential diagnosis for a 49-year-old patient with vasculitis on chronic high-dose steroids who has brain lesions and lung masses on chest imaging. I am assuming the patient is immunocompromised from chronic high-dose corticosteroids and the "brain lesions" are enhancing mass lesions on MRI.

Explore differential diagnoses

Generate and refine differential diagnoses fast. Expert AI highlights key clinical considerations, risk factors, and red flags grounded in trusted sources.

Progressive asymmetric weakness with areflexia in diabetic pt post-URI, ddx for rapidly evolving neuropathy?

UpToDate Expert AI product screenshot showing a table response about Acute immune-mediated polyn... with column Diagnosis containing "Guillain-Barre syndrome" and "CIDP", followed by column Key tests to support or refute containing "CSF and electrodiagnostic studies; consider brain or spine MRI when central features are present." and "Electrodiagnostic studies showing early axonal involvement." respectively
  • Full text description
    UpToDate Expert AI product screenshot showing a table response about Acute immune-mediated polyn... with column Diagnosis containing "Guillain-Barre syndrome" and "CIDP", followed by column Key tests to support or refute containing "CSF and electrodiagnostic studies; consider brain or spine MRI when central features are present." and "Electrodiagnostic studies showing early axonal involvement." respectively.

Make informed treatment decisions

Review treatment options, potential adverse effects, dosing considerations, and supporting evidence all within the conversation.

Outpatient, antibiotics, CAP, penicillin allergy.

UpToDate Expert AI product screenshot showing information for the drug Cefpodoxime with adult dosing information and related diseases like COPD and Otitis media; an AI generated response is also shown, stating: For a patient with a severe penicillin allergy (lgE-mediated or severe delayed), respiratory fluoroquinolone monotherapy is recommended
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    UpToDate Expert AI product screenshot showing information for the drug Cefpodoxime with adult dosing information and related diseases like COPD and Otitis media; an AI generated response is also shown, stating: For a patient with a severe penicillin allergy (lgE-mediated or severe delayed), respiratory fluoroquinolone monotherapy is recommended

Earn CME credits through everyday practice

Seamlessly earn CME while exploring clinical questions as part of your everyday workflow.

Show me the adult cardiac arrest algorithm.

UpToDate Expert AI product screenshot showing a CPR flow chart which starts with Start CPR: given oxygen and attach monitor/defibrillator -> Rhythm shockable? -> followed by additional options depending on yes or no selection. Also contains a text box indicating that CME 0.5 is accrued.
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    UpToDate Expert AI product screenshot showing a CPR flow chart which starts with “Start CPR: given oxygen and attach monitor/defibrillator", which then leads to “Rhythm shockable?”, followed by additional options depending on a yes or no selection. Also contains a text box indicating that CME 0.5 is accrued.

Get access to UpToDate Expert AI

Find flexible options for individual subscribers and healthcare organizations. 

Personal subscription options

UpToDate Expert AI is included in select personal UpToDate subscriptions. Availability may vary by country and subscription type.
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Hospitals and health systems

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