Drug Referential Content and Tools

The drug and drug interactions databases in UpToDate add another level of knowledge to clinical practice and help improve the quality and safety of care. In this section, learn how to search and navigate drug referential content, how to use the drug interactions tool, and how to utilize a hospital formulary integrated into UpToDate.

Drug Database

UpToDate topics deliver real-world evidence-based insights and recommendations to support you when making appropriate drug decisions for your patients. With our drug monographs — each containing details for adult, pediatric, and geriatric populations — you are equipped to make confident decisions for each unique patient. The same editorial team develops the drug topics in UpToDate and the more extensive drug information found in Lexicomp. This means the content you see when treating the patient tightly aligns with what is used by nurses, pharmacists, and other care team members who use Lexicomp. This synergy alleviates unnecessary back and forth communication when discrepancies arise between disconnected resources. And it helps patients, because they receive clear, consistent instructions and guidance throughout their journey.

Drug Database
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UpToDate contains more than 7,300 unique adult, pediatric, and international drug entries provided by Lexicomp®.

Additional information

  • Find and Navigate a Drug Topic

    UpToDate provides access to foundational content from the leading drug information resource, Lexicomp, including information on drug dosing, interactions, adverse effects, and other drug-related content.

    Searching a drug name will return drug information topics and other UpToDate topics containing information related to that drug.

    warfarin drug search


    Drug information topics are structured similarly to clinical topics, with a topic outline displayed at the left side of the page. Click on a heading in the topic outline to go directly to a desired section of the topic. Click on a linked reference number (either within the body of the topic or in the References section at the bottom of the topic) to display the Medline abstract for that reference.

    warfarin drug information page 

    Drug Information can also be accessed within the “Contents” dropdown in the blue toolbar on the top left of the screen.

    drug information drop down 

    View a detailed list of drug information topics within the linked sections.

    list of drug information topics

Downloads and related links

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