The trusted evidence-based resource to answer clinical questions

Each patient is unique, and every decision counts. With medicine growing more complex and evidence changing rapidly, it is critical that you have a clinical decision support resource you know you can trust and that is proven to improve patient outcomes.

Providing clarity when you need it most


As a clinician, you find yourself at the intersection of complexity and uncertainty – when the next steps are unclear, and you must make decisions based on the best evidence available to you. This is where UpToDate excels as a clinical decision support resource. We deliver the evidence powered by clinical expertise from the world’s leading physicians — not just for the routine cases, but for the complex and unclear.

Our authors and contributors bring deep domain expertise in the topic discussed and collaborate with our physician editors and peer reviewers to deliver evidence and recommendations that are rich in nuance, yet still clear and actionable. And we deliver it all with technology that helps you quickly get to the answers you need.

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See the research

More than 80 research studies show that widespread use of UpToDate is associated with improved outcomes and hospital performance.

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Meet our global experts

With UpToDate, it’s like having the world’s leading physicians in the room with you whenever you need guidance.

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Hear from our clinician users

UpToDate is the go-to resource for clinicians around the world when they need answers, evidence, and expertise they know they can trust.

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UpToDate provides evidence-based, point-of-care clinical decision support to help you make care decisions with confidence.

case study - neonatal diabetes mellitus
Using deep insights and evidence to solve a diagnostic puzzle.
Learn how UpToDate helped a pediatric resident diagnose a rare case of neonatal diabetes mellitus.
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