Biologically-Responsive Hybrid Biomaterials: A Reference for Material Scientists and Bioengineers

This pioneering reference book provides a comprehensive review on synthesis, characterization, structure-activity, 3D assembly/fabrication, host response, and the emerging applications of conjugate hybrid biomaterials.

There is no doubt that biologically-responsive conjugate biomaterials play a key role in the design of biologics and medical devices. Conjugation of synthetic materials with cell-responsive biologically-active molecules, in addition to providing structural support and release of biomolecules in the regenerating region, can provide the signaling factors required to initiate the cascade of cell migration, adhesion, differentiation, maturation, growth factor modulation, maintenance of matrix integrity, and tissue morphogenesis. Nanoparticles conjugated with ligands that preferentially interact with cell surface receptors in the tumor environment have the potential to drastically improve bioavailability, selectivity and residence time of the chemotherapeutic agent in the tumor microenvironment, while limiting their peripheral toxicity. Multivalent presentation of tumor-associated antigens on a targeted delivery system containing T and B cell epitopes can result in strong, long-lasting,

Platform:

OvidSP

Publisher:

World Scientific Publishing Co, Inc.

Product Type:

Book

Author:

Jabbari, Esmaiel.; Khademhosseini, Ali

ISBN:

978-9-81-429567-3

Specialty:

• Biomedical Engineering

Language:

English

Edition:

1st

Pages:

432

Publication Year:

2010

Doody Core Title Score:

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