Our in-house physician deputy editors, all of whom receive training in clinical epidemiology, oversee the integrity and consistency of this review process and work closely with the expert authors. We review evidence from:
- More than 425 peer-reviewed journals
- Society guidelines, clinical databases, and clinical trials for important new medical findings
- Databases including Medline, The Cochrane Library, Clinical Evidence, and the Agency for Healthcare Research and Quality
- Guidelines and trial reports from leading agencies like the U.S. Centers for Disease Control and Prevention, the European Medicines Agency, and the World Health Organization
- Proceedings of major scientific meetings
- More than 7,300 world-renowned experts with extensive clinical experience assist our editors in applying evidence to specific patient situations.
Graded recommendations allow you to make decisions even when evidence is not clear.
Our recommendations are based on a synthesis of evidence, including that obtained from clinical trials as well as clinical experience. The recommendations are categorized based on the GRADE system, which communicates the strength of the recommendation (strong or weak), and the quality of the evidence on which it is based (high, medium, or low). Gordon Guyatt, MD, a cofounder of the system, provides regular training to our physician editors about evidence-based medicine and grading.